Illustration of osteoarthritis of a knee joint
Osteoarthritis (OA) is the most common form of arthritis in the U.S. Approximately 27 million adults have reported being diagnosed with OA by their doctor. While the cause of OA is unknown, it occurs when cartilage in joints breaks down over time. Often called “wear and tear” arthritis, OA is most commonly found in the knees, hips, hands, or spine, though it can occur in any joint.
Quick facts about OA
- One in 2 people in the U.S. will experience some form of OA in their lifetime.
- OA is much more common in women than men.
- OA accounts for more than 50% of arthritis cases in the U.S. (nearly 27 million of the 46 million adults who have reported doctor-diagnosed arthritis).
Symptoms of OA
The most noticeable symptom of OA is a feeling of pain in or around the joint. Other symptoms include:
- Tenderness and stiffness in the joint
- Loss of flexibility or range of motion
- Grating sensation or sound in the joint, also known as crepitus
You might notice some of these feelings or sounds even when performing everyday activities like climbing stairs, getting dressed, or going shopping. If you do, talk to your doctor about it. Go to Partnering with Your Doctor, where you'll find helpful information about talking to your doctor.
Causes of OA
While the causes of OA are still unknown, the risk of developing OA increases as you get older. You are also at risk if you:
- Have someone in your family who has OA
- Are overweight
- Repetitively overuse a joint
- Have previously injured a joint
Treatment of OA
While there's no way to reverse the cartilage loss of OA, there are many ways to treat the pain. You may be able to manage OA pain effectively with an integrated treatment approach that includes positive lifestyle changes and anti-inflammatory drugs like NSAIDs.
Just one 200mg CELEBREX a day can provide 24-hour relief for many with arthritis pain and inflammation.* Learn more about CELEBREX.
*Individual results may vary. This dosing is for osteoarthritis.
CELEBREX is indicated for the relief of the signs and symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, and for the management of acute pain in adults.
Important Safety Information
All prescription NSAIDs, like CELEBREX, ibuprofen, naproxen, and meloxicam have the same cardiovascular warning. They may all increase the chance of heart attack or stroke that can lead to death. This chance increases if you have heart disease or risk factors for it, such as high blood pressure or when NSAIDs are taken for long periods.
CELEBREX should not be used right before or after certain heart surgeries.
Serious skin reactions, or stomach and intestine problems such as bleeding and ulcers, can occur without warning and may cause death. Patients taking aspirin and the elderly are at increased risk for stomach bleeding and ulcers.
Tell your doctor if you have:
* A history of ulcers or bleeding in the stomach or intestines
* High blood pressure or heart failure
* Kidney or liver problems
CELEBREX should not be taken in late pregnancy.
Do not take CELEBREX if you have bleeding in the stomach or intestine, or you’ve had an asthma attack, hives, or other allergic reactions to aspirin, any other NSAID medicine or certain drugs called sulfonamides.
Life threatening allergic reactions can occur with CELEBREX. Get help right away if you’ve had swelling of the face or throat or trouble breathing.
Prescription CELEBREX should be used exactly as prescribed at the lowest dose possible and for the shortest time needed.