Indications:

CELEBREX is indicated for the relief of the signs and symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, and for the management of acute pain in adults.

Important Safety Information:

Like all prescription NSAIDs, CELEBREX may increase the chance of heart attack or stroke that can lead to death. This chance increases if you have heart disease or risk factors for it, such as high blood pressure or when NSAIDs are taken for long periods.

CELEBREX should not be used right before or after certain heart surgeries.

Serious skin reactions, or stomach and intestine problems such as bleeding and ulcers, can occur without warning and may cause death. Patients taking aspirin and the elderly are at increased risk for stomach bleeding and ulcers.

Tell your doctor if you have:
* A history of ulcers or bleeding in the stomach or intestines
* High blood pressure or heart failure
* Kidney or liver problems

CELEBREX should not be taken in late pregnancy.

Do not take CELEBREX if you've had an asthma attack, hives, or other allergic reactions to aspirin, any other NSAID medicine, or certain drugs called sulfonamides.

Life threatening allergic reactions can occur with CELEBREX. Get help right away if you've had swelling of the face or throat or trouble breathing.

Prescription CELEBREX should be used exactly as prescribed at the lowest dose possible and for the shortest time needed.

For more information about CELEBREX and other NSAIDs, please see the Medication Guide.
For further information on CELEBREX, please see the full Prescribing Information.