Understanding the risks and benefits of NSAIDs is important. All NSAIDs, including CELEBREX, help relieve arthritis pain, but only you and your doctor can decide which one is right for you. An NSAID like CELEBREX might be an arthritis treatment option.

CELEBREX relieves arthritis pain, stiffness, and inflammation. Just one 200-mg dose provides 24-hour relief.

In clinical studies, a lower percentage of patients on CELEBREX reported indigestion, abdominal pain, and nausea versus prescription ibuprofen and naproxen.

If you are taking low-dose aspirin for your heart and need an NSAID pain reliever, CELEBREX can be used because it doesn’t interfere with the effects of low-dose aspirin. Taking low-dose aspirin may not reduce the cardiovascular risk associated with NSAID use. With any NSAID, including CELEBREX, patients also taking aspirin are at an increased risk for stomach bleeding and ulcers. CELEBREX is not a substitute for aspirin in preventing heart attack or stroke.

Based on the available data, the FDA stated that, for certain patients, the benefits of CELEBREX outweigh the risks. But only you and your doctor can make that decision.

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Important Safety Information
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Important Safety Information:

Like all prescription NSAIDs, CELEBREX may increase the chance of a heart attack or stroke that can lead to death. It should not be used right before or after certain heart surgeries.

Serious skin reactions or stomach and intestine problems, such as bleeding and ulcers, can occur without warning and may cause death.

Patients taking aspirin and the elderly are at increased risk for stomach bleeding and ulcers.

Tell your doctor if you:
* Are pregnant
* Have a history of ulcers or bleeding in the stomach or intestines
* Have high blood pressure or heart failure
* Have kidney or liver problems

People with aspirin-sensitive asthma or allergic reactions due to aspirin or other arthritis medicines or certain drugs called sulfonamides should not take CELEBREX.

Prescription CELEBREX should be used exactly as prescribed at the lowest dose possible and for the shortest time needed.

For more information about CELEBREX and other NSAIDs, please see the Medication Guide.
For further information on CELEBREX, please see the full Prescribing Information.

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