Do all prescription NSAIDs have the same cardiovascular warning?
All prescription NSAIDs, including ibuprofen, naproxen, meloxicam, and CELEBREX, share the same cardiovascular warning: they may increase the chance of heart attack or stroke, which can lead to death.

Do all NSAIDs have the same warnings for serious stomach and intestine side effects?
All prescription NSAIDs have the same warning for serious stomach and intestine problems, such as ulcers and bleeding, which can occur without warning and may cause death.

Are there any differences in other stomach side effects between the NSAIDs?
In clinical studies, a lower percentage of patients on CELEBREX reported indigestion, abdominal pain, and nausea versus prescription ibuprofen and naproxen.

How long has CELEBREX been on the market?
CELEBREX was approved in December 1998, and has been on the market for over 10 years.

How do I know if CELEBREX is right for me?
Whether CELEBREX, or any NSAID, is right for you can depend on your medical history and the severity and type of your pain. Only you and your doctor can decide the best option for you.

Can CELEBREX be taken with low-dose aspirin?
If you are taking low-dose aspirin for your heart and need an NSAID pain reliever, CELEBREX can be used because it doesn’t interfere with aspirin’s antiplatelet effect. However, taking low-dose aspirin may not reduce the cardiovascular risk associated with NSAID use. With any NSAID, including CELEBREX, patients also taking aspirin are at an increased risk for stomach bleeding and ulcers. CELEBREX is not a substitute for aspirin in preventing heart attack or stroke.

Important Safety Information:

Like all prescription NSAIDs, CELEBREX may increase the chance of a heart attack or stroke that can lead to death. It should not be used right before or after certain heart surgeries.

Serious skin reactions or stomach and intestine problems, such as bleeding and ulcers, can occur without warning and may cause death.

Patients taking aspirin and the elderly are at increased risk for stomach bleeding and ulcers.

Tell your doctor if you:
* Are pregnant
* Have a history of ulcers or bleeding in the stomach or intestines
* Have high blood pressure or heart failure
* Have kidney or liver problems

People with aspirin-sensitive asthma or allergic reactions due to aspirin or other arthritis medicines or certain drugs called sulfonamides should not take CELEBREX.

Prescription CELEBREX should be used exactly as prescribed at the lowest dose possible and for the shortest time needed.

For more information about CELEBREX and other NSAIDs, please see the Medication Guide.
For further information on CELEBREX, please see the full Prescribing Information.

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